NIPT (Non Invasive Prenatal Testing)

You can now have your Harmony test performed at home by an experienced nurse

Harmony test london

Harmony NIPT test process

Harmony test london

What is NIPT?

NIPT (non-invasive prenatal testing) looks at fragments of DNA in your blood during pregnancy to provide accurate information about the likelihood of chromosomal conditions that can impact your baby’s health.

When can it be performed?

NIPT can be performed as early as 10 weeks of pregnancy. You are advised to have at least a viability scan prior to the NIPT test .

Who can be eligible for NIPT?

NIPT is not only for high risk pregnancy.

The International Society for Prenatal Diagnosis (ISPD) considers NIPT as appropriate to be offered to all pregnant women as a primary screening test.

Difference between NIPT and First trimester screening

First trimester screening combines the results of biochemical blood tests with the structural findings measured under ultrasound to predict the chance that your baby has a chromosomal or other structural abnormality.

NIPT is a genetic test that analyses your baby’s DNA fragments that are circulating in your bloodstream to detect the most common chromosomal abnormalities.

What about diagnostics tests?

The Harmony prenatal test is a non-invasive prenatal test (NIPT) based on cell-free DNA analysis and is considered a prenatal screening test, not a diagnostic test.

Because NIPT is a prenatal screening test it cannot rule out the possibility of chromosomal conditions. In the case of a high probability result, your care provider may offer follow up testing to confirm a diagnosis. 

Prenatal diagnostic tests such as amniocentesis or chorionic villus sampling (CVS) require collection of the baby’s cells in the amniotic fluid or the placenta with a needle and are therefore considered invasive. Diagnostic tests provide a definitive answer; however, they pose a slight chance of loss of pregnancy due to the procedure itself.

Is it safe?

NIPT is performed with a simple blood draw from the mother therefore this is a safe procedure.

What is tested with the Harmony test ?

Harmony screens for the most common chromosomal conditions such as trisomy 21 (Down syndrome), trisomy 18, trisomy 13, sex chromosome aneuploidies (Turner syndrome and Klinefelter syndrome)

Harmony test also provides the option to opt-in for the screening of 22q11.2 microdeletion (DiGeorge syndrome ) and for the reporting of the fetal gender.

How accurate is the Harmony test?

The Harmony prenatal test has been shown to have superior accuracy in a direct comparison to traditional first trimester screening in over 15,000 women. It is much less likely to give a false-positive or false negative result. That means there will be much less chance your doctor would recommend follow-up testing such as amniocentesis.

How long does the test take?

Your results are sent to your doctor in 5–8 business days from the day your blood sample was collected.

1

Your consultant refers your for the Harmony test

2

You book your test with us via email or whatsapp

3

Your test is done at home by an experienced nurse

4

You get your report within 8 days via your consultant

Note

In rare cases (less than 3%), the laboratory is unable to obtain a result from the first sample. This can occur in samples where there is not enough of the baby’s DNA. Further testing may be required (at no additional cost), and could therefore delay the result. If no result is obtained from the second sample, you may be offered a re-test free-of-charge. In patients where a re-test is requested, approximately two-thirds produce a result on the second sample. If no result is possible, a full refund may be offered.

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